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Logo for company Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc. (KPTI)

NASDAQ Currency in USD
$302.00
-$1.55
-0.51%
Last Update: 18 Jul 2026, 15:49
$3.30bn
Market Cap
-20.04
P/E Ratio (TTM)
Forward Dividend Yield
$207.65-$380.34
52 Week Range

KPTI Stock Price Chart

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KPTI Company Profile

Discover essential business fundamentals and corporate details for Karyopharm Therapeutics Inc. (KPTI) to support your stock research and investment decisions.

Sector

Healthcare

Industry

Biotechnology

IPO Date

6 Nov 2013

Employees

279.00

CEO

Richard A. Paulson

Description

Karyopharm Therapeutics Inc. is a pharmaceutical company that has already brought products to market, focusing on identifying, advancing, and selling medications designed to disrupt nuclear export pathways. These drugs are primarily aimed at treating cancer and various other illnesses. The company's strategy involves researching, creating, and marketing innovative Selective Inhibitor of Nuclear Export (SINE) compounds, which operate by attaching to and deactivating the nuclear export protein XPO1. Their leading therapeutic, XPOVIO, holds approvals for several critical applications in adult patients: it is prescribed in combination with bortezomib and dexamethasone for multiple myeloma; alongside dexamethasone for those with heavily pretreated multiple myeloma; and as a standalone treatment for relapsed or refractory diffuse large B-cell lymphoma. Karyopharm has also established a licensing partnership with the Menarini Group, granting them rights to develop and market NEXPOVIO for human oncology indications across Europe (including the United Kingdom), Latin America, and other global regions. Furthermore, the company's oral SINE compounds are specifically engineered to promote the accumulation of various tumor suppressor and growth-regulating proteins within the cell nucleus. Established in 2008, Karyopharm Therapeutics Inc. maintains its principal offices in Newton, Massachusetts.

KPTI Financial Timeline

Browse a chronological timeline of Karyopharm Therapeutics Inc. corporate events including earnings releases, dividend announcements, and stock splits.

Upcoming earnings on 10 Aug 2026

EPS estimate is -$1.31, while revenue estimate is $33.12m.

Earnings released on 14 May 2026

EPS came in at -$1.24 surpassing the estimated -$1.45 by +14.48%, while revenue for the quarter reached $35.07m , beating expectations by +11.68%.

Earnings released on 12 Feb 2026

EPS came in at -$2.23 surpassing the estimated -$2.26 by +1.33%, while revenue for the quarter reached $34.08m , missing expectations by -2.92%.

Earnings released on 3 Nov 2025

EPS came in at -$3.82 falling short of the estimated -$3.47 by -10.09%, while revenue for the quarter reached $44.04m , beating expectations by +4.71%.

Earnings released on 11 Aug 2025

EPS came in at -$4.32 falling short of the estimated -$3.80 by -13.68%, while revenue for the quarter reached $37.93m , missing expectations by -4.13%.

Earnings released on 12 May 2025

EPS came in at -$2.77 surpassing the estimated -$4.21 by +34.20%, while revenue for the quarter reached $30.02m , missing expectations by -14.54%.

Stock split effective on 26 Feb 2025

Shares were split 1 : 15 , changing the number of shares outstanding and the price per share accordingly.

Earnings released on 19 Feb 2025

EPS came in at -$3.60 surpassing the estimated -$3.90 by +7.69%, while revenue for the quarter reached $30.54m , missing expectations by -19.26%.

Earnings released on 5 Nov 2024

EPS came in at -$3.90 surpassing the estimated -$4.05 by +3.70%, while revenue for the quarter reached $38.78m , beating expectations by +1.54%.

Earnings released on 6 Aug 2024

EPS came in at -$3.00 surpassing the estimated -$4.35 by +31.03%, while revenue for the quarter reached $42.79m , beating expectations by +18.26%.

Earnings released on 8 May 2024

EPS came in at -$4.80 surpassing the estimated -$4.95 by +3.03%, while revenue for the quarter reached $33.13m , missing expectations by -3.90%.

Earnings released on 29 Feb 2024

EPS came in at -$5.40 falling short of the estimated -$4.35 by -24.14%, while revenue for the quarter reached $33.75m , missing expectations by -4.67%.

Earnings released on 2 Nov 2023

EPS came in at -$4.50 falling short of the estimated -$4.20 by -7.14%, while revenue for the quarter reached $36.01m , missing expectations by -3.41%.

Earnings released on 2 Aug 2023

EPS came in at -$4.35 surpassing the estimated -$5.10 by +14.71%, while revenue for the quarter reached $37.58m , beating expectations by +4.36%.

Earnings released on 4 May 2023

EPS came in at -$4.50 surpassing the estimated -$5.10 by +11.76%, while revenue for the quarter reached $38.70m , beating expectations by +5.73%.

Earnings released on 15 Feb 2023

EPS came in at -$6.45 falling short of the estimated -$5.10 by -26.47%, while revenue for the quarter reached $33.58m , missing expectations by -2.46%.

Earnings released on 3 Nov 2022

EPS came in at -$6.75 surpassing the estimated -$8.40 by +19.64%, while revenue for the quarter reached $36.15m , beating expectations by +3.78%.

Earnings released on 4 Aug 2022

EPS came in at -$9.30 surpassing the estimated -$9.45 by +1.59%, while revenue for the quarter reached $39.68m , beating expectations by +10.33%.

Earnings released on 5 May 2022

EPS came in at -$7.95 surpassing the estimated -$9.45 by +15.87%, while revenue for the quarter reached $47.67m , beating expectations by +38.54%.

Earnings released on 8 Feb 2022

EPS came in at $6.90 surpassing the estimated -$6.00 by +215.00%, while revenue for the quarter reached $126.27m , beating expectations by +139.54%.

Earnings released on 3 Nov 2021

EPS came in at -$10.34 falling short of the estimated -$10.19 by -1.47%, while revenue for the quarter reached $37.69m , beating expectations by +46.08%.

Earnings released on 5 Aug 2021

EPS came in at -$10.64 surpassing the estimated -$10.79 by +1.39%, while revenue for the quarter reached $22.60m , meeting expectations.

KPTI Stock Performance

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