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Logo for company Spyre Therapeutics, Inc.

Spyre Therapeutics, Inc. (SYRE)

NASDAQ Currency in USD
$16.20
+$0.02
+0.12%
Last Update: 11 Sept 2025, 20:00
$978.50M
Market Cap
-7.75
P/E Ratio (TTM)
Forward Dividend Yield
$10.91 - $40.26
52 Week Range

SYRE Stock Price Chart

Explore Spyre Therapeutics, Inc. interactive price chart. Choose custom timeframes to analyze SYRE price movements and trends.

SYRE Company Profile

Discover essential business fundamentals and corporate details for Spyre Therapeutics, Inc. (SYRE) to support your stock research and investment decisions.

Sector

Healthcare

Industry

Biotechnology

IPO Date

7 Apr 2016

Employees

73.00

CEO

Cameron Turtle DPHIL,

Description

Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies. In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.

SYRE Financial Timeline

Browse a chronological timeline of Spyre Therapeutics, Inc. corporate events including earnings releases, dividend announcements, and stock splits.

Upcoming earnings on 6 May 2026

Upcoming earnings on 25 Feb 2026

Upcoming earnings on 6 Nov 2025

EPS estimate is -$0.75.

Earnings released on 5 Aug 2025

EPS came in at -$0.49 surpassing the estimated -$0.73 by +32.88%.

Earnings released on 8 May 2025

EPS came in at -$0.74 surpassing the estimated -$0.76 by +2.63%.

Earnings released on 27 Feb 2025

EPS came in at -$0.81 surpassing the estimated -$0.89 by +8.99%.

Earnings released on 7 Nov 2024

EPS came in at -$1.36 falling short of the estimated -$0.80 by -70.00%.

Earnings released on 7 Aug 2024

EPS came in at -$0.86 surpassing the estimated -$0.90 by +4.44%.

Earnings released on 9 May 2024

EPS came in at -$1.20 falling short of the estimated -$0.90 by -33.33%.

Earnings released on 29 Feb 2024

EPS came in at -$2.28 falling short of the estimated -$0.48 by -375.00%, while revenue for the quarter reached $1.04M , beating expectations by +373.64%.

Earnings released on 9 Nov 2023

EPS came in at -$9.34 falling short of the estimated -$0.84 by -1.01K%.

Stock split effective on 8 Sept 2023

Shares were split 1 : 25 , changing the number of shares outstanding and the price per share accordingly.

Earnings released on 11 Aug 2023

EPS came in at -$1.66 surpassing the estimated -$4.50 by +63.11%, while revenue for the quarter reached $688.00K , beating expectations by +247.47%.

Earnings released on 31 Mar 2023

EPS came in at -$4.89 falling short of the estimated -$4.50 by -8.57%, while revenue for the quarter reached $198.00K , beating expectations by +7.61%.

Earnings released on 30 Dec 2022

EPS came in at -$7.20 falling short of the estimated -$5.71 by -26.14%, while revenue for the quarter reached $168.00K , beating expectations by +26.00%.

Earnings released on 29 Sept 2022

EPS came in at -$4.84 surpassing the estimated -$6.25 by +22.57%, while revenue for the quarter reached $174.00K , missing expectations by -16.48%.

Earnings released on 29 Jun 2022

EPS came in at -$6.79 surpassing the estimated -$7.95 by +14.57%, while revenue for the quarter reached $625.00K , missing expectations by -11.91%.

Earnings released on 30 Mar 2022

EPS came in at -$9.26 , while revenue for the quarter reached $1.36M .

Earnings released on 30 Dec 2021

EPS came in at -$10.36 falling short of the estimated -$8.54 by -21.33%, while revenue for the quarter reached $3.64M , beating expectations by +128.84%.

Earnings released on 29 Sept 2021

EPS came in at -$7.72 , while revenue for the quarter reached $1.40M .

Earnings released on 29 Jun 2021

EPS came in at -$2.60 , while revenue for the quarter reached $13.70M .

Earnings released on 31 Mar 2021

EPS came in at -$6.94 .

Earnings released on 31 Dec 2020

EPS came in at -$9.47 .

Earnings released on 30 Sept 2020

EPS came in at -$7.24 .

SYRE Stock Performance

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